Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.23/523
Título: Giant pilomatricoma in a patient with tuberous sclerosis, both diagnosed in the adult life.
Autor: Resende, CI
Gomes, J
Duarte, ML
Brito, C
Palavras-chave: Pilomatrixoma
Neoplasias da Pele
Doenças do Cabelo
Esclerose Tuberosa
Data: 2013
Editora: BMJ
Citação: BMJ Case Rep. 2013 Aug 29;2013. pii: bcr2013010382.
Resumo: Pilomatricoma is a relatively common benign skin neoplasm originating from the hair follicle matrix cells. β-Catenin is a subunit of the cadherin protein complex. It acts as an intracellular signal transducer that influences cell differentiation and proliferation. This protein was recently involved in the formation of hair follicle-related tumours, including pilomatricomas. Tuberous sclerosis (TS) is an inherited neurocutaneous disease, which is characterised by pleomorphic features involving many organs, hamartomas in multiple organ systems and by the fact that it is usually diagnosed early in life. We reported a case of a Caucasian patient with TS and a giant pilomatricoma, both diagnosed in the adult life.
Peer review: yes
URI: http://comum.rcaap.pt/handle/123456789/4812
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