Repository logo
 
Publication

Pulmonary Kaposi sarcoma and disseminated Mycobacterium genavense infection in an HIV-infected patient

2015Journal article Open access
Simple item page
dc.contributor.authorTribuna, C
dc.contributor.authorÂngela, C
dc.contributor.authorEira, I
dc.contributor.authorCarvalho, A
dc.date.accessioned2016-09-16T14:46:49Z
dc.date.available2016-09-16T14:46:49Z
dc.date.issued2015
dc.description.abstractWe report a case of Kaposi sarcoma (KS) and disseminated infection by Mycobacterium genavense in a 40-year-old HIV-positive man with CD4+ T-cell count 5/µL. He presented with anorexia, diarrhoea, cachexia and multiple firm violaceous nodules distributed over the face, neck and upper and lower extremities. Biopsy of a skin nodule was performed, confirming KS. Immunoperoxidase staining for human herpesvirus 8 was strongly positive. Endoscopic examination revealed erosive duodenopathy. Multiple biopsy samples showed numerous acid-fast bacilli at direct microscopic examination. Real-time PCR (RT-PCR) identified M. genavense. A CT scan showed diffuse pulmonary infiltrates with a 'tree-in-bud' appearance, striking splenomegaly and abdominal lymphadenopathy. A bronchoscopy was performed, revealing typical Kaposi's lesions in the upper respiratory tract. RT-PCR of bronchial aspirate identified M. genavense and Pneumocystis jirovecii. Despite treatment with highly active antiretroviral therapy, antimycobacterial therapy and trimethoprim/sulfamethoxazole, the outcome was fatal.pt_PT
dc.identifier.citationBMJ Case Rep. 2015 Oct 8;2015. pii: bcr2015211683.pt_PT
dc.identifier.doi10.1136/bcr-2015-211683pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.23/1099
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.subjectInfecções Oportunistas Relacionadas com a SIDApt_PT
dc.subjectInfecções por VIHpt_PT
dc.subjectSarcoma de Kaposipt_PT
dc.subjectInfecções por Micobactéria não Tuberculosapt_PT
dc.subjectSarcoma, Kaposipt_PT
dc.titlePulmonary Kaposi sarcoma and disseminated Mycobacterium genavense infection in an HIV-infected patientpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.startPagebcr2015211683pt_PT
oaire.citation.volume2015pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Pulmonary Kaposi sarcoma.pdf
Size:
1.6 MB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

HB - MED INT - Artigos