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Acute Alithiasic Cholecystitis and Human Herpes Virus Type-6 Infection: First Case

dc.contributor.authorGomes, MM
dc.contributor.authorAntunes, H
dc.contributor.authorLobo, AL
dc.contributor.authorBranca, F
dc.contributor.authorCorreia-Pinto, J
dc.contributor.authorMoreira-Pinto, J
dc.date.accessioned2016-07-15T13:30:21Z
dc.date.available2016-07-15T13:30:21Z
dc.date.issued2016
dc.description.abstractA three-year-old male child presented with erythematous maculopapular nonpruritic generalized rash, poor feeding, vomiting, and cramping generalized abdominal pain. He was previously healthy and there was no family history of immunologic or other diseases. On examination he was afebrile, hemodynamically stable, with painful palpation of the right upper quadrant and positive Murphy's sign. Laboratory tests revealed elevated inflammatory markers, elevated aminotransferase activity, and features of cholestasis. Abdominal ultrasound showed gallbladder wall thickening of 8 mm with a positive sonographic Murphy's sign, without gallstones or pericholecystic fluid. Acute Alithiasic Cholecystitis (AAC) was diagnosed. Tests for underlying infectious causes were negative except positive blood specimen for Human Herpes Virus Type-6 (HHV-6) by polymerase chain reaction. With supportive therapy the child became progressively less symptomatic with gradual improvement. The child was discharged on the sixth day, asymptomatic and with improved analytic values. Two months later he had IgM negative and IgG positive antibodies (1/160) for HHV-6, which confirmed the diagnosis of previous infection. In a six-month follow-up period he remains asymptomatic. To the best of our knowledge, this represents the first case of AAC associated with HHV-6 infection.pt_PT
dc.identifier.citationCase Rep Pediatr. 2016;2016:9130673.pt_PT
dc.identifier.doi10.1155/2016/9130673pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.23/1059
dc.language.isoporpt_PT
dc.peerreviewedyespt_PT
dc.subjectHerpesvirus Humano 6pt_PT
dc.subjectColecistitept_PT
dc.titleAcute Alithiasic Cholecystitis and Human Herpes Virus Type-6 Infection: First Casept_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage4pt_PT
oaire.citation.startPage9130673pt_PT
oaire.citation.volume2016pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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