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Synchronous intraductal papillary mucinous neoplasm and a pancreatic neuroendocrine tumor: more than a coincidence?

dc.contributor.authorCosta, JM
dc.contributor.authorCarvalho, SB
dc.contributor.authorSoares, JB
dc.date.accessioned2017-09-08T14:35:44Z
dc.date.available2017-09-08T14:35:44Z
dc.date.issued2017-09
dc.description.abstractBACKGROUND: Although the association between intraductal papillary mucinous neoplasm of the pancreas (IPMN) and pancreatic neuroendocrine tumor (PNET) has been increasingly reported, whether this association is real or coincidence remains unclear. We report a case of synchronous IPMN and a PNET which were diagnosed preoperatively and discuss the tumorigenesis, clinicopathological features and management of these rare tumors based on the published literature. CASE REPORT: A 56-year-old male was incidentally diagnosed with a 14 mm branch duct IPMN and a 3.6 mm non-functional PNET during an evaluation due to persistent upper abdominal pain via endoscopic ultrasound. Close follow-up of the patient was decided as the IPMN had no worrisome features. A review of twenty-two previously reported cases of synchronous IPMN and PNET indicated that: a) only seven cases were diagnosed preoperatively; b) abdominal pain was the main presenting symptom; c) IPMN was the dominant tumor and presented with low grade dysplasia; d) the PNET was small and non-functional and had an indolent behavior; and e) only one case underwent radiologic follow-up. DISCUSSION: IPMN are associated with other pancreatic and extrapancreatic malignancies. Thus, the entire pancreatic parenchyma should be examined closely during the evaluation of an IPMN in order to exclude other pancreatic lesions, for example, a PNET.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationRev Esp Enferm Dig. 2017 Sep;109(9):663-635pt_PT
dc.identifier.doi10.17235/reed.2017.5003/2017pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.23/1211
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.subjectCarcinoma Ductal Pancreáticopt_PT
dc.subjectAdenocarcinomapt_PT
dc.subjectColangiocarcinomapt_PT
dc.titleSynchronous intraductal papillary mucinous neoplasm and a pancreatic neuroendocrine tumor: more than a coincidence?pt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue9pt_PT
oaire.citation.startPage663-635pt_PT
oaire.citation.volume109pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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