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Hospital Resource Utilization and Treatment Cost of Skeletal-Related Events in Patients with Metastatic Breast or Prostate Cancer: Estimation for the Portuguese National Health System

2011Journal article Open access
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dc.contributor.authorFélix, J
dc.contributor.authorAndreozzi, V
dc.contributor.authorSoares, M
dc.contributor.authorBorrego, P
dc.contributor.authorGervásio, H
dc.contributor.authorMoreira, A
dc.contributor.authorCosta, L
dc.contributor.authorMarcelo, F
dc.contributor.authorPeralta, F
dc.contributor.authorFurtado, I
dc.contributor.authorPina, F
dc.contributor.authorAlbuquerque, C
dc.contributor.authorSantos, A
dc.contributor.authorPassos-Coelho, JL
dc.contributor.authorPortuguese Group for the Study of Bone Metastases
dc.date.accessioned2013-11-15T15:42:08Z
dc.date.available2013-11-15T15:42:08Z
dc.date.issued2011
dc.description.abstractBACKGROUND: Skeletal-related events (SREs) occur frequently in patients with bone metastases as a result of breast (BC) and prostate (PC) cancers. They increase both morbidity and mortality and lead to extensive health-care resource utilization. METHODS: Health care resource utilization by BC/PC patients with at least one SRE during the preceding 12 months was assessed through retrospective chart review. SRE-treatment costs were estimated using the Portuguese Ministry of Health cost database and analyzed using generalized linear models. RESULTS: This study included 152 patients from nine hospitals. The mean (SD) annual SRE-treatment cost per patient was €5963 (€3646) and €5711 (€4347), for BC (n=121) and PC (n=31) patients, respectively. Mean cost per single episode ranged between €1485 (radiotherapy) and €13,203 (spinal cord compression). Early onset of bone metastasis (P = 0.03) and diagnosis of bone metastases at or after the occurrence of the first SRE (P < 0.001) were associated with higher SRE-treatment costs. CONCLUSION: These results reveal the high hospital SRE-treatment costs, highlighting the need for early diagnosis and treatment, and identify key factors determining the economic value of therapies for patients with skeletal metastases.por
dc.identifier.citationValue Health. 2011;14(4):499-505.por
dc.identifier.urihttp://hdl.handle.net/10400.23/550
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherElsevierpor
dc.subjectPortugalpor
dc.subjectNeoplasias da Mamapor
dc.subjectNeoplasias dos Ossospor
dc.subjectNeoplasias da Próstatapor
dc.subjectMetástasespor
dc.subjectRecursos em Saúdepor
dc.subjectCustos Hospitalarespor
dc.titleHospital Resource Utilization and Treatment Cost of Skeletal-Related Events in Patients with Metastatic Breast or Prostate Cancer: Estimation for the Portuguese National Health Systempor
dc.typejournal article
dspace.entity.typePublication
rcaap.rightsopenAccesspor
rcaap.typearticlepor

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