From juvenile parkinsonism to encephalitis lethargica, a new phenotype of post-streptococcal disorders: case report.

Beleza, P; Soares-Fernandes, J; Jordão, MJ; Almeida, F

http://hdl.handle.net/10400.23/448

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Abstract(s)

We report the case of a 16-year-old boy presented with a mild akinetic-rigid parkinsonism shortly after a post-streptococcal infection. After stopping corticoids, he had a rapid neurological deterioration to a fatal encephalitis lethargica-like syndrome. Serum analysis demonstrated consistently elevated anti-streptolysin-O. This case illustrates a new severe phenotype in the spectrum of the post-streptococcal disorders. This etiology should be considered in the differential diagnosis of a movement disorder with a rapid detrimental evolution.