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Impact of atrial fibrillation type during acute coronary syndromes: Clinical features and prognosis.

dc.contributor.authorGalvão-Braga, C
dc.contributor.authorRamos, V
dc.contributor.authorMartins, J
dc.contributor.authorArantes, C
dc.contributor.authorAbreu, G
dc.contributor.authorVieira, C
dc.contributor.authorSalgado, A
dc.contributor.authorGaspar, A
dc.contributor.authorAzevedo, P
dc.contributor.authorÁlvares-Pereira, M
dc.contributor.authorMagalhães, S
dc.contributor.authorMarques, J
dc.date.accessioned2015-07-01T15:02:00Z
dc.date.available2015-07-01T15:02:00Z
dc.date.issued2015
dc.description.abstractINTRODUCTION: Atrial fibrillation (AF) is widely recognized as an adverse prognostic factor during acute myocardial infarction, although the impact of AF type - new-onset (nAF) or pre-existing (pAF) - is still controversial. OBJECTIVES: To identify the clinical differences and prognosis of nAF and pAF during acute coronary syndromes (ACS). METHODS: We performed a retrospective observational cohort study including 1373 consecutive patients (mean age 64 years, 77.3% male) admitted to a single center over a three-year period, with a six-month follow-up. RESULTS: AF rhythm was identified in 14.5% patients, of whom 71.4% presented nAF and 28.6% pAF. When AF types were compared, patients with nAF more frequently presented with ST-elevation ACS (p=0.003). Patients with pAF, in turn, were older (p=0.032), had greater left atrial diameter (p=0.001) and were less likely to have significant coronary lesions (p=0.034). Regarding therapeutic strategy, nAF patients were more often treated by rhythm control during hospital stay (p<0.001) and were less often anticoagulated at discharge (p=0.001). Compared with the population without AF, nAF was a predictor of death during hospital stay in univariate (p<0.001) and multivariate analysis (OR 2.67, p=0.047), but pAF was not. During follow-up, pAF was associated with higher mortality (p=0.014), while nAF patients presented only a trend towards worse prognosis. CONCLUSIONS: AF during the acute phase of ACS appears to have a negative prognostic impact only in patients with nAF and not in those with pAF.por
dc.identifier.citationRev Port Cardiol. 2015 Jun;34(6):403-10.por
dc.identifier.urihttp://hdl.handle.net/10400.23/925
dc.language.isoengpor
dc.peerreviewedyespor
dc.subjectSíndrome Coronária Agudapor
dc.subjectFibrilhação Auricularpor
dc.subjectPrognósticopor
dc.titleImpact of atrial fibrillation type during acute coronary syndromes: Clinical features and prognosis.por
dc.title.alternativeImpacto do tipo de fibrilhac¸ão auricular no contexto das síndromes coronárias agudas: características clínicas e prognósticopor
dc.typejournal article
dspace.entity.typePublication
rcaap.rightsopenAccesspor
rcaap.typearticlepor

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