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Management and Treatment of Glucocorticoid-Induced Hyperglycemia

dc.contributor.authorParedes, S
dc.contributor.authorAlves, M
dc.date.accessioned2017-01-20T12:09:43Z
dc.date.available2017-01-20T12:09:43Z
dc.date.issued2016-09
dc.description.abstractINTRODUCTION: Glucocorticoids have been associated to several side effects, specially a diabetogenic action, the most common and representative effect. Glucocorticoid-induced hyperglycemia is a common medical condition, with general associated morbidity and mortality. MATERIAL AND METHODS: It was performed a literature review about the management and treatment of glucocorticoid-induced hyperglycemia. RESULTS: Through numerous not quite fully understood mechanics, glucocorticoids promote hyperglycemia in non-diabetic patients and worsen diabetes control in diabetic individuals. Glucocorticoid-induced hyperglycemia presents key patterns, enhanced in the postprandial period and scheduled-dependent. Despite the existence of guidelines for hyperglycemia treatment in non-critic hospitalized and non-hospitalized patients, there are no guidelines respecting glucocorticoid-induced hyperglycemia. Nevertheless, it is known that glucocorticoid-induced hyperglycemia is complex and demanding, requiring a specific approach. Indeed, glucocorticoid-induced hyperglycemia treatment depends on the glucocorticoid used, its dose, frequency and schedule. Furthermore, the scheme of treatment previously used by diabetic individuals also influences the choice of the new scheme. DISCUSSION AND CONCLUSION: The authors reviewed the glucocorticoid induced-hyperglycemia thematic and propose strategies to approach and treat glucocorticoid induced-hyperglycemia in diabetic and non-diabetic individuals. This review is expected to be useful in different settings and crosswise to all medical specialties.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationActa Med Port. 2016 Sep;29(9):556-563.pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.23/1135
dc.language.isoporpt_PT
dc.peerreviewedyespt_PT
dc.subjectGlucocorticóides/efeitos adversospt_PT
dc.subjectHiperglicemia/diagnósticopt_PT
dc.subjectHiperglicemia/induzida quimicamentept_PT
dc.subjectHiperglicemia/ tratamentopt_PT
dc.titleManagement and Treatment of Glucocorticoid-Induced Hyperglycemiapt_PT
dc.title.alternativeAbordagem e Tratamento da Hiperglicemia Induzida por Glicocorticóidespt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue9pt_PT
oaire.citation.startPage556-563pt_PT
oaire.citation.volume29pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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