Publication
A whole genome screen for association with multiple sclerosis in Portuguese patients
| dc.contributor.author | Santos, M | |
| dc.contributor.author | Pinto-Basto, J | |
| dc.contributor.author | Rio, ME | |
| dc.contributor.author | Sá, MJ | |
| dc.contributor.author | Valença, A | |
| dc.contributor.author | Sá, A | |
| dc.contributor.author | Dinis, J | |
| dc.contributor.author | Figueiredo, J | |
| dc.contributor.author | Bigotte de Almeida, L | |
| dc.contributor.author | Coelho, I | |
| dc.contributor.author | Sawcer, S | |
| dc.contributor.author | Setakis, E | |
| dc.contributor.author | Compston, A | |
| dc.contributor.author | Sequeiros, J | |
| dc.contributor.author | Maciel, P | |
| dc.date.accessioned | 2013-07-18T11:56:37Z | |
| dc.date.available | 2013-07-18T11:56:37Z | |
| dc.date.issued | 2003 | |
| dc.description.abstract | Multiple sclerosis (MS) is common in Europe affecting up to 1:500 people. In an effort to identify genes influencing susceptibility to the disease, we have performed a population-based whole genome screen for association. In this study, 6000 microsatellite markers were typed in separately pooled DNA samples from MS patients (n=188) and matched controls (n=188). Interpretable data was obtained from 4661 of these markers. Refining analysis of the most promising markers identified 10 showing potential evidence for association. | por |
| dc.identifier.citation | J Neuroimmunol. 2003;143(1-2):112-5. | por |
| dc.identifier.uri | http://hdl.handle.net/10400.23/463 | |
| dc.language.iso | eng | por |
| dc.peerreviewed | yes | por |
| dc.publisher | Elsevier | por |
| dc.subject | Predisposição Genética para Doença | por |
| dc.subject | Testes Genéticos | por |
| dc.subject | Esclerose Múltipla | por |
| dc.title | A whole genome screen for association with multiple sclerosis in Portuguese patients | por |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.awardURI | info:eu-repo/grantAgreement/WT/057097 | |
| oaire.awardURI | info:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBD%2F9111%2F2002/PT | |
| oaire.fundingStream | 057097 | |
| oaire.fundingStream | SFRH | |
| project.funder.identifier | http://doi.org/10.13039/100010269 | |
| project.funder.identifier | http://doi.org/10.13039/501100001871 | |
| project.funder.name | Wellcome Trust | |
| project.funder.name | Fundação para a Ciência e a Tecnologia | |
| rcaap.rights | openAccess | por |
| rcaap.type | article | por |
| relation.isProjectOfPublication | ac29bf67-e3f1-4037-9e16-dc86baa1fd32 | |
| relation.isProjectOfPublication | b3263814-6c6c-4e23-8d2a-e11b396ce834 | |
| relation.isProjectOfPublication.latestForDiscovery | ac29bf67-e3f1-4037-9e16-dc86baa1fd32 |