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Long-term mortality analysis in Parkinson's disease treated with deep brain stimulation.

2014Journal article Open access
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dc.contributor.authorRocha, S
dc.contributor.authorMonteiro, A
dc.contributor.authorLinhares, P
dc.contributor.authorChamadoira, C
dc.contributor.authorBastos, MA
dc.contributor.authorReis, C
dc.contributor.authorSousa, C
dc.contributor.authorLima, J
dc.contributor.authorRosas, MJ
dc.date.accessioned2014-06-06T13:19:02Z
dc.date.available2014-06-06T13:19:02Z
dc.date.issued2014
dc.description.abstractBackground. Few data have been published regarding long-term mortality in patients with Parkinson's disease treated with DBS. Methods. This study analyzed long-term mortality rates, causes, and correlates in PD patients treated with DBS. Results. 184 consecutive patients were included; mean follow-up was 50 months. Fifteen deaths occurred (total 8.15%, annual mortality rate 1.94%). Mean age at disease onset and at surgery was 48 ± 2.4 and 63 ± 1.6 years, respectively. Mean disease duration until death was 21 ± 7.8 years. Most deaths related to stroke, myocardial infarction, other vascular/heart disorders, or severe infection; one suicide was recorded. Deceased PD patients were mostly male and had lower motor benefit after DBS, but univariate analysis failed to show significant differences regarding gender and motor benefit. Survival was 99% and 94% at 3 and 5 years. Conclusions. Long-term survival is to be expected in PD patients treated with DBS, possibly higher than previously expected. Death usually supervenes due to vascular events or infection.por
dc.identifier.citationParkinsons Dis. 2014;2014:717041.por
dc.identifier.urihttp://hdl.handle.net/10400.23/612
dc.language.isoengpor
dc.publisherHindawipor
dc.subjectEstimulação Encefálica Profunda/ mortalidadepor
dc.subjectDoença de Parkinsonpor
dc.titleLong-term mortality analysis in Parkinson's disease treated with deep brain stimulation.por
dc.typejournal article
dspace.entity.typePublication
rcaap.rightsopenAccesspor
rcaap.typearticlepor

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