Publication
The dynamics of the stress neuromatrix
dc.contributor.author | Sousa, N | |
dc.date.accessioned | 2016-05-04T11:34:35Z | |
dc.date.available | 2016-05-04T11:34:35Z | |
dc.date.issued | 2016-03 | |
dc.description.abstract | Stressful stimuli in healthy subjects trigger activation of a consistent and reproducible set of brain regions; yet, the notion that there is a single and constant stress neuromatrix is not sustainable. Indeed, after chronic stress exposure there is activation of many brain regions outside that network. This suggests that there is a distinction between the acute and the chronic stress neuromatrix. Herein, a new working model is proposed to understand the shift between these networks. The understanding of the factors that modulate these networks and their interplay will allow for a more comprehensive and holistic perspective of how the brain shifts 'back and forth' from a healthy to a stressed pattern and, ultimately, how the latter can be a trigger for several neurological and psychiatric conditions. | pt_PT |
dc.identifier.citation | Mol Psychiatry. 2016 Mar;21(3):302-12. | pt_PT |
dc.identifier.doi | 10.1038/mp.2015.196 | pt_PT |
dc.identifier.uri | http://hdl.handle.net/10400.23/1018 | |
dc.language.iso | eng | pt_PT |
dc.peerreviewed | yes | pt_PT |
dc.subject | Cérebro/fisiologia | pt_PT |
dc.subject | Stress Psicológico | pt_PT |
dc.title | The dynamics of the stress neuromatrix | pt_PT |
dc.type | journal article | |
dspace.entity.type | Publication | |
rcaap.rights | openAccess | pt_PT |
rcaap.type | article | pt_PT |