Browsing by Author "Ferreira, L"
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- Adenopatias mediastínicas, que diagnóstico?Publication . Pacheco, C; Cruz, J; Alves, D; Rolo, R; Ferreira, L; Cunha, J
- Awareness campaign at World COPD dayPublication . Pacheco, C; Cruz, JF; Lacerda, C; Ferreira, L; Cunha, J
- Caracterização da Consulta de Apneia do Sono do Serviço de Pneumologia do Hospital de BragaPublication . Pacheco, C; Cruz, J; Alves, D; Rolo, R; Ferreira, L; cunha, J
- Chronic granulomatous disease associated with common variable immunodeficiency - 2 clinical casesPublication . Pacheco, C; Morais, A; Rolo, R; Ferreira, L; Nabiço, R; Cunha, JINTRODUCTION: Chronic granulomatous disease associated with common variable immunodeficiency (GD-CVID), although well documented, is rare. Granulomatous lesions can affect several organs and are histologically indistinguishable from sarcoidosis. CLINICAL CASES: Case 1: A 39-year-old male patient with CVID, asymptomatic although with thrombocytopenia and mediastinal-hilar adenopathies. GD-CVID was diagnosed by bone marrow biopsy. Progressive clinical and radiological improvement was obtained with corticotherapy. Case 2: A 38-year-old male patient with CVID, suffered from asthenia, anorexia, myalgia, lower limbs edemas, and dry cough. He had mediastinal and bilateral hilar adenopathies within which biopsy revealed non-necrotizing granulomatous infiltrate. A spontaneous resolution was detected after 9 months of evolution. CONCLUSION: GD-CVID is rare and can mimetize other pathologies, namely, sarcoidosis; it should therefore be publicized and discussed so that it becomes a general clinical knowledge.
- Dia Mundial da DPOC – Campanha de sensibilização no Hospital de BragaPublication . Pacheco, C; Cruz, JF; Lacerda, C; Iglesias, L; Ferreira, L; Cunha, L
- Doença de Still, uma entidade rara mas há que pensar nela!Publication . Burmester, I; Ramalho, J; Sotto-Mayor, J; Regadas, MJ; Ferreira, L; Oliveira e Silva, A
- Impacto da DPOC na qualidade de vida – a utilização do CATPublication . Pacheco, C; Cruz, JF; Alves, D; Rolo, R; Ferreira, L; Cunha, J
- Melanoma maligno associado a nevo melanocíticoPublication . Gomes, J; Parente, J; Ferreira, L; Viana, I; Vale, EObjectives: To determine clinical and histopathological differences between melanoma associated with nevus (MAN) and de novo melanoma (MN). Methods: Retrospective study of all cases of cutaneous melanoma diagnosed between 2001 and 2009 in Centro de Dermatologia Médico-Cirúrgica de Lisboa. Results: Of the 397 melanomas included, 52.6% were of feminine sex and 47.4% of the masculine. Of these melanomas only 9.3% were histologically associated with nevus, with discrete predominance of cases in the feminine sex (54%, p=0,033). In the group of the MAN the average of ages was slightly inferior (56,5 vs 59,3 years, p=0,577). The trunk was the preferential localization of all the melanomas (42.1%, p=0,005). Histologically the superficial spreading subtype was more frequently associated with MAN. The MAN were thinner than the MN (1,42 versus 2,13 mm, p=0,030), specially in the feminine sex (0,99mm, p=0,031). The Breslow tumor thickness and the presence of ulceration had a significant statistical correlation with the metastatic spread and the mortality by melanoma. Conclusions: The majority of the melanomas seem to arise de novo. In our study, factors that were significantly associated with MAN include feminine sex, trunk location, younger age, inferior Breslow thickness and superficial spreading subtype.
- Mixoma endobrônquico: Caso clínicoPublication . Rolo, R; Pereira, R; Eisele, L; Ferreira, L; Nogueira, R; Cunha, JINTRODUCTION: Pulmonary myxoma is an extremely rare benign neoplasm. It is mostly parenchymal but may occasionally occur within the tracheobronchial tree. There are very few reports of endobronchial myxoma. CASE REPORT: We describe a case of endobronchial myxoma in a 40-year-old female patient with a history of asthma and repeated right-sided pneumonia. Thoracic computed tomography (CT) showed medium lobe atelectasis. Fiber optic bronchoscopy revealed a polypoid, well-circumscribed tumor, causing total obstruction of the medium lobe bronchus. Biopsy of the mass was non-diagnostic. Further study included a positron emission tomography (PET) which demonstrated low metabolic activity of the tumor and no evidence of neoplasia in other location. The patient was submitted to a medium lobectomy and microscopic examination of the tumor revealed myxoid stroma with lobulated pattern, elongated and stellate cells, compatible with myxoma. CONCLUSION: Pulmonary myxoma is extraordinary rare and endobronchial location is very few reported in medical literature.
- Múltiplos nódulos pulmonares, que diagnóstico? – Caso clínico XIPublication . Pacheco, C; Cruz, J; Rolo, R; Ferreira, L; Cunha, J