Browsing by Author "Oliveira, M"
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- Efeitos da Exposição Pré-natal à Dexametasona na Mucosa GástricaPublication . Leão, P; Oliveira, M; Botelho, C; Mariz, J; Roque, S; Correia-Neves, M; Sousa, N
- Giant recurrent retroperitoneal liposarcoma initially presenting as inguinal hernia: Review of literature.Publication . Leão, P; Vilaça, S; Oliveira, M; Falcão, JINTRODUCTION: Liposarcomas comprise around 15% of soft tissue tumors. These tumors of mesodermal origin arise as single tumors, present one histologic type and diverse locations (including the retroperitoneum). Diagnosis of liposarcomas of retroperitoneum is difficult because of this unspecific presentation and in 50-100% of the cases there is recurrence from residual tissue. PRESENTATION OF CASE: An 86 year old male patient was admitted in 1996 due to a right and voluminous inguinal hernia. During the herniaplasty, a right paratesticular tumor was isolated and removed. The histologic exam revealed a well-differentiated liposarcoma. A CT scan was performed and a large abdominal mass was detected. The patient underwent a laparotomy and an incomplete resection of the tumor was achieved. After the surgery the patient remained asymptomatic during a long period. Nine years later, the patient underwent another laparotomy with partial removal of the giant recurrent retroperitoneal liposarcoma. CONCLUSION: The purpose of this publication is to report the recurrence of giant retroperitoneal liposarcoma, which is an unusual presentation in surgery today. Furthermore, we would like to emphasize the long-term survival of this patient despite partial resection and the possibility of performing a re-resection in this type of cases.
- Head-to-head comparison of two online nomograms for prostate biopsy outcome predictionPublication . Oliveira, M; Marques, V; Carvalho, AP; Santos, ALEVEL OF EVIDENCE: 2b. What's known on the subject? and What does the study add? In recent years, several nomograms were developed in an effort to decrease the number of unnecessary prostate biopsies. The European SWOP-PRI and the North American PCPT are among the most popular. However, evidence on the relative predictive accuracy is lacking. A head-to-head comparison on the diagnostic accuracy of two previously validated prostate cancer risk predictors on biopsy confirmed the superiority of these tools over PSA alone. Moreover, in the studied population, the European SWOP-PRI proved to be more accurate than the North American PCPT-CRC. OBJECTIVE: To compare the diagnostic accuracy of two previously validated prostate cancer risk predictors on biopsy. PATIENTS AND METHODS: In total, 390 consecutive patients submitted to 10-core systematic transrectal prostate biopsy at our institution were included in this retrospective study. External validation of a European (European Randomized Study of Screening for Prostate Cancer derived Prostate Risk Indicator; SWOP-PRI) and a North American (Prostate Cancer Prevention Trial Cancer Risk Calculator; PCPT-CRC) nomogram was performed. The predictive accuracy of these online available nomograms was calculated based on the area under the curve derived from receiver-operator characteristic curves and then compared using the DeLong method. RESULTS: Both tools were confirmed to be superior to prostate-specific antigen alone. Moreover, the SWOP-PRI (77.9%) displays a 7.96% increase in the predictive accuracy compared to the PCPT-CRC (69.9%) in a statistically significant fashion (P=0.002). CONCLUSIONS: The results obtained in the present study confirm the utility of nomograms with respect to biopsy outcome prediction in patients with suspicion of prostate cancer. In the current sample of patients, the European-based nomogram appears to be more accurate than the North American nonogram, which lacks information regarding prostate volume and prostatic ultrasonographic lesions. • To our knowledge, this is the first study to compare the accuracy of these popular risk calculators in a specific population.
- Pieloureterite cística em doente em choque séptico: caso clínico e revisão da literaturaPublication . Oliveira, M; Cabral-Ribeiro, J; Mendes, M; Ribeiro dos Santos, AA pieloureteriste cística é uma patologia benigna rara, caracterizada pela presença de cistos suburoteliais. A persistência de estímulos irritativos a nível do urotélio e a subsequente resposta inflamatória crónica foram implicadas no seu desenvolvimento. Este distúrbio, cujo diagnóstico decorre de um achado radiológico incidental típico, caracterizado pela presença de múltiplas imagens de subtracção ao longo da árvore pieloureteral, encontra-se frequentemente associado a patologia litiásica e infecciosa do tracto urinário. No entanto, outras causas para estes achados característicos devem ser considerados, particularmente os tumores uroteliais e a tuberculose genitourinária. A propósito de um caso de pieloureterite cística diagnosticado numa doente em choque séptico, revemos as suas principais características clínicas e estratégias terapêuticas.
- Prenatal Exposure Dexamethasone Alters the Cytokine Profile: Implications for Peptic DiseasePublication . Leão, P; Oliveira, M; Botelho, CM; Mariz, J; Lamas, N; Sousa, N
- Prosthetic Esophageal Transmural Erosion After Mesh HiatoplastyPublication . Leão, P; Carneiro, T; Oliveira, M; Luís, D; Rolanda, C; Machado, A; Pereira, P; Macedo, G; Gomes, A
- The Morphologic Changes in the Gastric Wall Associated with Prenatal Dexamethasone AdministrationPublication . Leão, P; Oliveira, M; Sousa, N