Browsing by Author "Pereira, J"
Now showing 1 - 5 of 5
Results Per Page
Sort Options
- Diversity in anti-N-methyl-D-aspartate receptor encephalitis: case-based evidencePublication . Pinho, J; Rocha, J; Rodrigues, M; Pereira, J; Maré, R; Ferreira, C; Lourenço, E; Beleza, PAntibodies against N-methyl-D-aspartate receptor (NMDAR) are identified in the form of immune-mediated encephalitis in which typical manifestations include neuropsychiatric symptoms, seizures, abnormal movements, dysautonomia and hypoventilation. The authors report two cases of anti-NMDAR encephalitis with different presentations and patterns of progression. The first patient presented with status epilepticus and later developed psychosis, pyramidal signs and diffuse encephalopathy. The second patient presented with acute psychosis followed a week later by seizures, dystonia, rigidity, oromandibular dyskinesias and dysautonomia. Possible mechanisms responsible for the clinical manifestations of this disease are discussed in light of recently described additional clinical and laboratory findings.
- Probable acute disseminated encephalomyelitis due to Haemophilus influenzae meningitisPublication . Beleza, P; Ribeiro, M; Pereira, J; Jordão, MJ; Almeida, FWe report the case of a 17-year-old male on long-term steroid therapy for minimal lesion glomerulopathy who, after an upper respiratory infection, presented with Haemophilus influenzae type b meningitis. Twenty-four hours later he developed depression of consciousness which progressed to coma and left hemiparesis. Brain magnetic resonance imaging (MRI) revealed multiple lesions (hyperintense on T2 and slightly hypointense on Tl) involving mainly white matter suggestive of inflammation. MRI features were compatible with acute disseminated encephalomyelitis (ADEM), although a differential diagnosis included cerebritis or vasculitis, secondary to bacterial meningitis. The patient was treated with high-dose steroids which resulted in a gradual improvement followed by complete clinical recovery. We propose a diagnosis of ADEM was the best diagnosis because of the radiological features and response to steroids. The occurrence of ADEM associated with acute meningitis, however rare, represents an important diagnostic challenge for the clinician.
- Takotsubo cardiomyopathy – a rare, but serious, complication of epileptic seizuresPublication . Rocha, J; Gonçalves, E; Vieira, C; Almeida, F; Pereira, JTakotsubo cardiomyopathy (TKC) is a reversible, yet potentially fatal, syndrome triggered by stressful conditions, including seizures, with increasing recognition in clinical practice. We report a TKC in a patient with unexplained sinus tachycardia and troponin elevation after generalized seizures.
- Takotsubo cardiomyopathy: a rare, but serious, complication of epileptic seizuresPublication . Rocha, J; Gonçalves, E; Vieira, C; Almeida, F; Pereira, J
- Vertebral osteoporotic fractures with height loss secondary to Cushing’s diseasePublication . Nogueira, C; Souto, SB; Rios, E; Pereira, J; Vinha, E; Freitas, P; Carvalho, D