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Browsing by Issue Date, starting with "2016-05"

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  • Eosinophilic Esophagitis
    Publication . Costa, S; Ferreira, M; Gonçalves, B; Gonçalves, R
    2016-05Journal article Open access Show more
  • Statin-related myotoxicity
    Publication . Fernandes, V; Santos, MJ; Pérez, A
    Statin therapy has a very important role in decreasing cardiovascular risk, and treatment non-compliance may therefore be a concern in high cardiovascular risk patients. Myotoxicity is a frequent side effect of statin therapy and one of the main causes of statin discontinuation, which limits effective treatment of patients at risk of or with cardiovascular disease. Because of the high proportion of patients on statin treatment and the frequency of statin-related myotoxicity, this is a subject of concern in clinical practice. However, statin-related myotoxicity is probably underestimated because there is not a gold standard definition, and its diagnosis is challenging. Moreover, information about pathophysiology and optimal therapeutic options is scarce. Therefore, this paper reviews the knowledge about the definition, pathophysiology and predisposing conditions, diagnosis and management of statin-related myotoxicity, and provides a practical scheme for its management in clinical practice.
    2016-05Journal article Open access Show more
  • Evaluation of the Psychometric Properties of the Mental Vulnerability Questionnaire in Undergraduate Students
    Publication . Sequeira, CA; Barbosa, EM; Nogueira, MJ; Sampaio, FM
    PURPOSE: Translate, adapt the language, and assess the psychometric properties of the Mental Vulnerability Questionnaire (MVQ) in a Portuguese population sample of young adults. DESIGN AND METHODS: A psychometric validation study was performed. The sample comprised 166 undergraduate students. Factor analysis was applied to extract three indicators. FINDINGS: The MVQ showed divergent validity with the Positive Mental Health Questionnaire (p < .001) and convergent validity with the Mental Health Inventory including five items (p < .001). Reliability was verified through the assessment of internal consistency, evidencing positive outcomes (Cronbach's α = 0.81). PRACTICE IMPLICATIONS: The MVQ shows psychometric properties enabling its adaptation to clinical practice and research, essential to an effective screening of mental vulnerability.
    2016-05-20Journal article Open access Show more