Publication
Leg ulcer as a manifestation of eosinophilic vasculitis in a patient with hepatitis C virus infection, medicated with pegylated interferon/ribavirin.
| dc.contributor.author | Resende, C | |
| dc.contributor.author | Pereira, T | |
| dc.contributor.author | Ventura, F | |
| dc.contributor.author | Brito, C | |
| dc.date.accessioned | 2015-07-01T14:45:52Z | |
| dc.date.available | 2015-07-01T14:45:52Z | |
| dc.date.issued | 2015 | |
| dc.description.abstract | Cryoglobulinaemic vasculitis is a complication of hepatitis C virus (HCV) infection, responding to treatment with pegylated interferon (peg-IFN)/ribavirin (RIB), but vasculitis may first appear after treatment with peg-IFN/RIB. A 35-year-old man with HCV infection presented to our department with a 2-month history of a 3.3×3 cm ulcer localised on the right shin, with a regular border, on a violaceous base. Histopathological examination revealed a leucocytoclastic vasculitis, rich in eosinophils. The patient had been treated with peg-IFN/RIB 10 months prior and treatment was discontinued after 2 months because of the appearance of arthralgias and neuropathy. Laboratory investigations revealed positive cryoglobulins, elevation of rheumatoid factor and reduction of C4 after treatment with peg-IFN/RIB. Dressings with a hydrocellular foam were placed and after 2 months the ulcer resolved. We presented this case because of the rarity of development of a cryoglobulinaemic vasculitis in a patient with HCV infection, previously treated with peg-IFN/RIB. | por |
| dc.identifier.citation | BMJ Case Rep. 2015 Jun 11;2015. pii: bcr2015209377. | por |
| dc.identifier.uri | http://hdl.handle.net/10400.23/922 | |
| dc.language.iso | eng | por |
| dc.peerreviewed | yes | por |
| dc.subject | Eosinofilia | por |
| dc.subject | Úlcera da Pele | por |
| dc.subject | Hepatitis C Crónica | por |
| dc.subject | Ribavirina | por |
| dc.subject | Interferon-alpha | por |
| dc.title | Leg ulcer as a manifestation of eosinophilic vasculitis in a patient with hepatitis C virus infection, medicated with pegylated interferon/ribavirin. | por |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| rcaap.rights | openAccess | por |
| rcaap.type | article | por |